WOHLER, FRIEDRICH (1800-1882), German chemist, was born at Eschersheim, near Frankfort-on-the-Main, on the 3131 of July 1800. In 1814 he began to attend the gymnasium at Frankfort, where he carried out experiments with his friend Dr J. J. C. Buch. In 1820 he entered Marburg University, and next year removed to Heidelberg, where he worked in Leopold Gmelin's laboratory. Intending to practise as a physician, he took his degree in medicine and surgery (1823), but was persuaded by Gmelin to devote himself to chemistry. He studied in Berzelius's laboratory at Stockholm, and there began a lifelong friendship with the Swedish chemist. On his return he had proposed to settle as a Privatdozent at Heidelberg, but accepted the post of teacher of chemistry in the newly established technical school (Gewerbeschule) in Berlin (1825), where he remained till 1831. Private affairs then called him to Cassel, where he soon became professor at the higher technical school. In 1836 he was appointed to the chair of chemistry in the medical faculty at Gottingen, holding also the office of inspector-general of pharmacies in the kingdom of Hanover. This professorship he held until his death on the 23rd of September 1882.
Wohjer had made the acquaintance of Liebig, his junior by three years, in 1825, and the two men remained close friends and allies for the rest of their lives. Together they carried out a number of joint researches. One of the earliest, if not the earliest, was the investigation, published in 1830, which proved the polymerism of cyanic and cyanuric acid, but the most famous were those on the oil of bitter almonds (benzaldehyde) and the radicle benzoyl (1832), and on uric acid (1837), which are of fundamental importance in the history of organic chemistry. But it was the achievement of Wohler alone, in 1828, to break down the barrier held to exist between organic and inorganic chemistry by artificially preparing urea, one of those substances which up to that time it had been thought could only be produced through the agency of " vital force." Most of his work, however, lay in the domain of inorganic chemistry. The isolation of the elementary bodies and the investigation of their properties was one of his favourite pursuits. In 1827 he obtained metallic aluminium as a fine powder, and in 1845 improved methods enabled him to get it in fully metallic globules. Nine years afterwards H. E. Samte-Claire Deville, ignorant of what he had done, adopted the same methods in his efforts to prepare the metal on an industrial scale; the result of Wohler 's claim of priority was that the two became good friends and joined in a research, published in 1856-1857, which yielded " adamantine boron." By the same method as had succeeded with aluminium (reduction of the chloride by potassium) Wohler in 1828 obtained metallic beryllium and yttrium. Later, in 1849, titanium engaged his attention, and, proving that what had up to that time passed as the metal was really a cyanonitride, he showed how the true metal was to be obtained. He also worked at the nitrides, and in 1857 with H. Buff carried out an inquiry on the compounds of silicon in which they prepared the previously unknown gas, silicon hydride or silicuretted hydrogen. A problem to which he returned repeatedly was that of separating nickel and cobalt from their ores and freeing them from arsenic; and in the course of his long laboratory practice he worked out numerous processes for the preparation of pure chemicals and methods of exact analysis.
The Royal Society's Catalogue enumerates 276 separate memoirs written by him, apart from 43 in which he collaborated with others.
In 1831 he published Grundriss der anorganischen Chemie, and in 1840 Grundriss der organischen Chemie, both of which went through many editions. Still more valuable for teaching purposes was his Mineralanalyse in Bcispielen (1861), which first appeared in 1853 as 1'raktische Ubungen in der chemischen Analyse. Chemists also had to thank him for translating three editions olthe Lehrbuch of Berzelius and all the successive volumes of the Jahresbericht into German from the original Swedish. He assisted Liebig and Poggendorff in the Handworterbuch der reinen und angewandten Chemie, and was jointeditor with Liebig of the Annalen der Chemie und Pharmacic.
A memoir by Hofmann appeared in the Ber. deut. chem. Geselisch. (1882), reprinted in Zur Erinnerung an vorangegangene Freunde (1888).
Note - this article incorporates content from Encyclopaedia Britannica, Eleventh Edition, (1910-1911)